In vivo neural activity of electrosensory pyramidal cells: Biophysical characterization and phenomenological modeling
Fig 6
Impact of stochastic synaptic input on the deterministic dynamics of the modified Hindmarsh-Rose (HR) model.
(A) Simulation of the voltage variable (V) of the modified HR model (top, teal), along with the slow adaptation variables z (red) and u (yellow), for an example ELL pyramidal cell receiving stochastic synaptic input (see Methods). (B) Raster spike trains obtained from simulations of the modified HR model for five different representing cells receiving stochastic synaptic input. These spike trains demonstrate the diversity of firing patterns across cells. (C) Statistical comparisons between experimental data (dark blue) and model simulations (teal) for spike train features of all recorded ELL pyramidal cells. From left to right: mean firing rate (meanfr; r = 0.97, ), burst fraction (burst frac; r = 0.86,
), mean (meanisi; r = 0.91,
), median (medianisi; r = 0.97,
), standard deviation (stdisi; r = 0.77,
) and the coefficient of variation (CVisi; r = 0.98,
) of ISIs, respectively.