In vivo neural activity of electrosensory pyramidal cells: Biophysical characterization and phenomenological modeling
Fig 3
Comparison of spike train features between intracellular recordings of a population of ELL pyramidal cells and their fitted model simulations.
(A) Membrane potential traces (top) and interspike interval (ISI) distribution (bottom) of a representative ELL pyramidal cell (dark blue, left) and its fitted model simulations (light blue, right). The recorded and simulated traces are 5 seconds long, showing sequences of bursts interspersed with isolated spikes and quiescent periods. Insets show zoomed-in examples of individual bursts from the recorded and simulated traces, highlighting the close match in spike shape and temporal organization within bursts. (B) Raster spike train plots from same recording in A (left) and their corresponding fitted simulations (right), separated into isolated spikes (green), burst spikes (red), and all spikes combined (blue). The model replicates the proportions and temporal organization of burst and isolated spikes observed in the recordings. (C) Scatter plots comparing key spike train features between recordings and simulations for all ELL pyramidal cells (n = 32). Panels from left to right: mean firing rate (meanfr; r = 0.99, ), burst fraction (burst frac; r = 0.88,
), mean (meanisi; r = 0.95,
), median (medianisi; r = 0.92,
), standard deviation (stdisi; r = 0.83,
) and the coefficient of variation (CVisi; r = 0.98,
) of ISIs, respectively.