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CrossLabFit: A novel framework for integrating qualitative and quantitative data across multiple labs for model calibration

Fig 6

Dynamics of influenza model for the two different approaches.

A comprehensive comparison of influenza model predictions for two approaches: the standard quantitative approach (purple) and using our CrossLabFit approach (turquoise). In the panel of plots, each column shows the viral dynamics V (panels (a) and (c)) and T cell dynamic T (panels (b) and (d)). The first row shows standard approach results using viral load data, highlighted by red circles. The last row integrates feasible window constraints for T. Color-coded solid line and shaded area illustrate the median and confidence interval, respectively, of the simulations obtained by estimating parameters using nonparametric bootstrapping, for each approach.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1013704.g006