Branch-specific gene discovery in cell differentiation using multi-omics graph attention
Fig 6
GRNS at different branch points.
A: Pre-branching network centered on MAML2, emphasizing its regulatory interactions with various genes. B: Branching point network focused on USP1. C: Post-branching phase 1 network with MAML2. D: Post-branching phase 2 network featuring MAML2, USP1, and SIPA1L1. In each panel, nodes represent genes, where key genes are highlighted at a larger size, and the thickness of edges reflects the strength of interactions. These networks reveal the dynamic rewiring of regulatory interactions at different stages of cell differentiation.