Regional heterogeneity in left atrial stiffness impacts passive deformation in a cohort of patient-specific models
Fig 7
(A) High-dimensional input parameter space reduction during HM. (B) Changes in the simulator outputs for each wave of history matching. The solid horizontal lines indicate the value of the output feature at ventricular end-systole (ES) estimated from the CT images. The shaded areas a represent 95% confidence interval on the observed output feature values. For dregion, the standard deviation is estimated from feature tracking and for ESV, the standard deviation is assumed to be ±5% EDV.