Optimization-based framework with flux balance analysis (FBA) and metabolic pathway analysis (MPA) for identifying metabolic objective functions
Fig 7
Predicted and experimental fermentation titers under single-objective function in the second stage of DMMM framework.
(A) The objective for the first 12 hr is butyrate and after that time is butanol. (B) The objective for the first 12 hr is butyrate and after that time is L-lactate.