Optimization-based framework with flux balance analysis (FBA) and metabolic pathway analysis (MPA) for identifying metabolic objective functions
Fig 4
A graphical representation of the syntrophic consortium model.
(A) The core metabolic pathways for the syntrophic consortium pathway of an engineered Cac & Clj to produce isopropanol, butanol, and ethanol from glucose and carbon dioxide. (B) Microbial metabolic networks spy plot of the iCAC802, iJL680, and their hybrid types of models. The dots represent that the corresponding metabolites are associated with the reactions.