Optimization-based framework with flux balance analysis (FBA) and metabolic pathway analysis (MPA) for identifying metabolic objective functions
Fig 3
Comparison of prediction errors in metabolite fluxes for C. acetobutylicum glucose fermentation in Experiment.
(A) Experiment 1, (B) Experiment 2. Three different weighting strategies were applied for flux prediction: (i) No weighting, (ii) Normalized experimental values as weights, (iii) TIObjFind-derived weights, and (iv) ObjFind method. Comparison of relative errors (%) in predicted fluxes for different weighting methods. Errors are calculated as .