Detecting polynucleotide motifs: Pentads, hexads, and beyond
Fig 3
Geometric definitions used in the evaluation of the candidate nucleotide.
The schematic illustrates the vectors and reference points employed in (A) Criterion 1 (connectivity), (B) Criterion 2 (tilt, defined by the angle between the candidate and tetrad base normal vectors), (C) Criterion 3 (distance, measured between the candidate and the tetrad centroid), and (D) Criterion 4 (height difference, calculated as the projection of candidate–centroid vectors onto tetrad base normals).