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Inference of weak-form partial differential equations describing migration and proliferation mechanisms in wound healing experiments on cancer cells

Fig 4

Root mean squared error (RMSE) calculated between experimental data and reaction-diffusion models from Jin et al. (blue), and a model obtained by PDE-constrained optimization following Variational System Identification (red) for each case with different initial number of seeded cells.

For the 18000 initial density data, the 4-term model was used. The model parameters inferred in this work are shown in Table 1.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1013607.g004