Multi-cellular network model predicts alterations in glomerular endothelial structure in diabetic kidney disease
Fig 9
Predicted changes in species in the multi-cellular protein interaction network (Fig 1) simulated using the time-dependent glucose control interventions (Fig 8) as input.
Predicted changes in A: activity and B: fenestration number and diameter from baseline without glucose intervention. Predicted changes in C: activity and D: fenestration number and diameter from baseline with glucose intervention applied at 4 weeks. Predicted changes in E: activity and F: fenestration number and diameter from baseline with glucose intervention applied at 10 weeks.