Multi-cellular network model predicts alterations in glomerular endothelial structure in diabetic kidney disease
Fig 4
Simulated fenestration number and diameter.
A: Simulated fenestration number fitted against observed mean fenestration density (black circles) in diabetic mice [10]. B: Simulated fenestration diameter fitted against observed mean fenestration width (black circles) in diabetic mice [10]. Blue-shaded regions show the 95% credible intervals of the predictions. Data are shown as mean ± standard deviation (SD). Individual fenestration width and density are also reported for each diabetic mouse (open circles). Initial values for fenestration diameter and number were assumed to be the same as baseline control mean data values of fenestration width and density (red squares) for healthy mice in Finch et al. [10].