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Multi-cellular network model predicts alterations in glomerular endothelial structure in diabetic kidney disease

Fig 3

Simulated glucose input concentration profiles (solid colorful lines) for a virtual mouse population (n = 100) to represent time-dependent inter-subject glucose variability.

Glucose was sampled n times in each time interval for 6–20 weeks by drawing from a normal distribution with mean and standard deviation from the data at the start of the corresponding time interval. The mean of the 100 profiles is shown as a solid black line. Glucose concentration data values are from Lee et al. [22] (blue circles) and Finch et al. [10] (red triangles). Data are shown as means ± standard deviations.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1013598.g003