Multiscale networks in Alzheimer’s disease identify brain hypometabolism as central across biological scales
Fig 12
Path analysis from the MRI layer in ADNI participants.
Depictions of the multilayer paths identified through Boolean simulations with the MRI layer as the starting point. The top paths, meeting criteria for negative controls, are presented for each input (MRI) - output (clinical phenotype) pair. Nodes within each layer are color-coded to reflect the node’s degree, indicating the frequency of its appearance in a path as a percentage of the total paths. For clarity, nodes are labeled numerically in the figure, and the corresponding variable names are provided in S1–S6 Tables. For detailed high-resolution paths, please refer to https://dsb-lab.github.io/network_paths/.