Differential equation modeling of cell population dynamics in skeletal muscle regeneration from single-cell transcriptomic data
Fig 4
Model predictions versus empirical data over a seven-day time course following muscle injury.
The solid black lines represent the trajectories obtained from the ODE model trained on the McKellar dataset. Empirical data points from the McKellar dataset are depicted as blue dots, with vertical bars indicating standard deviation across replicates. The e validation data from the De Micheli dataset are shown as red dots. The alignment of model predictions with the McKellar (training dataset) data points indicates the model’s accuracy, whereas consistency with the De Micheli (validation dataset) data points supports the model’s generalizability.