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Differential equation modeling of cell population dynamics in skeletal muscle regeneration from single-cell transcriptomic data

Fig 3

Cell-type population fractions from McKellar’s [33] and De Micheli’s [34] datasets.

Line graphs show the mean cell proportions across replicates of each cell type, as a fraction of all cell types included in our model. Each subplot corresponds to a different cell population in the model: N (neutrophils), M (monocytes), M1 (M1 macrophages), M2 (M2 macrophages), QSC (quiescent satellite cells), ASC (activated satellite cells), and Mc (myocytes). The empirical data do not include numbers for the dead cell types, Md and Nd.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1013575.g003