Mouse and human striatal projection neurons compared - somatodendritic arbor, spines and in silico analyses
Fig 7
Characterisation of the dendritic spines.
(A) Total spine area calculated in four reconstructed dendrites of mouse (red) and human (blue) neurons. Numbers correspond to the total number of spines per dendrite. (B) Total membrane area of dendritic spines and corresponding dendritic shafts in four reconstructed dendrites of mouse (red) and human (blue) neurons. (C) Dendritic spine density with distance from the soma. Parameters of the sigmoidal distribution (a, b, c) are given in the insets. (D) Proportion of spines located at the terminal dendritic sections (p = 0.000001). (E) Total number of spines per neuron (p = 0.67292) estimated for the repaired morphological reconstructions using spine density distributions from (C).