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Mouse and human striatal projection neurons compared - somatodendritic arbor, spines and in silico analyses

Fig 6

Reconstruction of the dendritic spines of human SPNs.

(A) Confocal photomicrograph of a horizontally projecting dendrite from an intracellular injected human SPN. Soma is shown with an arrow, and the rectangle depicts the region of interest. (B) Magnified ROI. (C) Same image as in B to illustrate the position of spines. (D) 3D reconstructions of spines showing a clear head. Spine head area is shown in red, spine neck length in white numbers (see S1 Table for full statistics). Scale bar (in D) is 16 μm in A and 5 μm in B-D.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1013569.g006