A compact model of Escherichia coli core and biosynthetic metabolism
Fig 4
Enzyme allocation predictions obtained with the model variant EC-iCH360 after adjusting the turnover parameters.
A: Predicted vs measured enzyme abundances for aerobic growth on eight different carbon sources. Each data point represents an enzyme-condition pair. A total of 325 data points corresponding to zero predictions (enzymes associated with zero-flux in the enzyme-constrained FBA solution for a given condition) were omitted from the plot. B: Geometric mean across conditions of predicted vs measured enzyme abundances. For each enzyme, the geometric mean was computed across the conditions with non-zero predicted abundance. A total of 27 data points, corresponding to enzymes with zero predictions across all conditions, were omitted from the plot.