Topology across scales on heterogeneous cell data
Fig 8
Clustering based on the topology of Endothelial cells in the human lung tissue.
A: Clustering based on the topological descriptor that attains the best Rand score when compared to the biological classification: percentiles of death values of degree 1 PH (alpha) of Endothelial cells. We observe that the Alveolitis samples are approximately separated from the other two stages, and the third cluster contains sparser samples. B: PCA of the topological descriptor from Endothelial cells that attains the best Rand score, with the clusters separated by black lines. C: For each sample, we plot the density of Endothelial cells. We indicate by color yellow, orange or red the stage of the disease, and by a label of color blue, green or purple the label in the clustering we obtain. The clustering corresponds approximately with thresholding by density.