Topology across scales on heterogeneous cell data
Fig 2
Lupus murine spleen cell centroid data.
A: Spatial distribution of cell centroids for the 25 cell types in lupus murine spleen CODEX data set. The data set consists of three healthy samples (BALBc-1, BALBc-2, BALBc-3), three samples in an early stage of the disease (MRL-4, MRL-5, MRL-6), two samples in an intermediate stage of the disease (MRL-7, MRL-8) and one sample in a late stage of the disease (MRL-9). B: Cell counts of the two types of pulp for each sample (entire slide) in tens of thousands of cells. C: Point clouds corresponding to the main parts of the spleen, the red pulp and the white pulp, for each sample, classified by disease stage. The white pulp forms compartments surrounded by the red pulp.