Natural variants of von Willebrand factor R1205 causing von Willebrand disease with accelerated von Willebrand factor clearance: In silico docking models and energetics of the interaction with both LRP1 and GpIb A1 domain
Table 4
Calculated ΔG of binding and the corresponding Kd values for the different VWF species and the N-terminal (H1-T266) domain of platelet GpIbα. The binding parameters were calculated by the PRODIGY program at T = 37 °C.