Natural variants of von Willebrand factor R1205 causing von Willebrand disease with accelerated von Willebrand factor clearance: In silico docking models and energetics of the interaction with both LRP1 and GpIb A1 domain

Fig 9

Values of ΔG of binding of the VWF forms to LRP1 as a function of VWF interface areas.

The slope of the linear regression is -0.006271 ± 0.001458 (p = 0.0231). The dashed lines represent the 95% confidence interval of the regression.