Natural variants of von Willebrand factor R1205 causing von Willebrand disease with accelerated von Willebrand factor clearance: In silico docking models and energetics of the interaction with both LRP1 and GpIb A1 domain
Fig 5
Molecular models obtained with I-TASSER and Haddock 2.4 programs of the adduct between p.R1205H-VWF and CCR IV of LRP1.
The VWF construct is shown in cyan, whereas the CCR IV of LRP1 is shown in pink. The interacting residues of the complex, all at distances comprised between 1.60 and 3.45 Å, are listed in S2 Table.