A coupling model of transcranial magnetic stimulation induced electric fields to neural state variables
Fig 2
Modeling flowchart of TMS coupling.
Electric fields enter as the input to a presynaptic populations, coupling directly to axons. The axonal delay kernel simulation quantifies the spatiotemporal output of the presynaptic populations as a density function r(z, t). This density function then enters the (synapto-) dendritic kernel simulation as an input to drive dynamics on the postsynaptic dendrites. Dendritic current entering the soma of the postsynaptic cells exits the model as the output measure, inheriting sensitivity to direction and dosing implicitly from the electric field input.