CytoSpatio: Learning cell type spatial relationships using multirange, multitype point process models
Fig 4
Evaluating tissue heterogeneity of cell type relationships.
Panels A to E show the top 2 principal components of the interaction coefficients of various trained models for different tile sizes. Symbol colors are blue for 2500x2500 tiles, orange for 5000x5000 tiles, green for each original image, and red x’s for all original images combined. Panel F illustrates the change of heterogeneity with the tile size for the five tissues. Note that the PC1 and PC2 axis limits in panels A to C are ten times smaller than those in Panels D and E since there is much less variation in those tissues.