iSTTC: A robust method for accurate estimation of intrinsic neural timescales from single-unit recordings
Fig 2
Schematic representation of spike time tiling coefficient calculation (STTC) and its adaptation for intrinsic timescale estimation (iSTTC).
(A) Schematic representation of STTC calculation, modified from [35] and [37]. STTC quantifies the correlation between spike trains A and B at a time interval .
(
) denotes the proportion of the signal within
of any spike in A (B), and
(
) the proportion of spikes in A (B) that fall within
of a spike in B (A). (B) Schematic illustration of iSTTC. Spike trains A and B are created by truncating and realigning the original spike train, after which the standard STTC formula is applied as in (A). (C) Schematic illustration of iSTTC applied on epoched data. Each trial is zero-padded prior to computing iSTTC across lags. Bottom left, violin plot displaying the absolute difference in estimated intrinsic timescales relative to the reference condition in which the zero-padding length equals the trial length T.