Integrated pan-cancer analysis of RNA binding protein HuR investigates its biomarker potential in prognosis, immunotherapy, and drug sensitivity
Fig 5
Effect of HuR on tumor immune cells across pan-cancer were estimated with Immune Score and ssGSEA immune Infiltration analysis.
(A) The variation of immune scores in different groups with high and low expression of HuR were displayed with violin plots. (B) ssGSEA immune infiltration analysis of HuR was accessed in different cancer types and showed in heatmap. Immune Score, an indicator for assessing the degree of immune cell infiltration in tumors was calculated with Estimate package. (B) Correlation between HuR and TIDE (Tumor Immune Dysfunction and Exclusion) score was displayed with boxplots across pan-cancer. *p < 0.05, **p < 0.01, ***p < 0.001.