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Effects of segmentation errors on downstream-analysis in highly-multiplexed tissue imaging

Fig 6

Effect of segmentation errors on phenotype assignments.

(A) Balanced accuracy between ground truth and perturbed data. (B) Confusion matrix showing the errors for the Gaussian mixture model (GMM) based phenotyping. The shown perturbation is according to state of the art (F1=90). Only values are shown. Color encodes the percentage of classified cells. For visual appearance, only off-diagonal elements are colored in. (C) Wu and Palmer distance for F1=90 based on the used gating strategy. Error bars indicate one median absolute deviation.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1013350.g006