Multi-context modeling of driver pathways reveals common and specific mechanisms across 23 cancer types
Fig 3
Pairwise comparison of cancer types similar in location or function.
(A, C, E) The top panels show the common gene sets between two cancers identified by EntCDP (A & B), and the bottom panels display the specific gene sets of cancer A relative to cancer B (A / B) or vice versa (B / A) by ModSDP. Only significant sets are shown. Numbers in the leftmost or rightmost columns denote the parameter K, which means the number of genes in each set. Genes in the highlighted rows are enriched in the signaling pathway at the bottom of each ladder table. (B, D, F) Regulation of genes involved in the signaling pathways shown in (A, C, E), respectively. Genes marked in purple are identified by EntCDP or ModSDP, while genes in green are not.