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Mathematical modelling of mechanotransduction via RhoA signalling pathways

Fig 5

Numerical simulation results showing , , and for the model in Eqs (3)–(6) for the axisymmetric shape and in the case of the 3D stimulus at a steady state at T = 100 s.

Four different scenarios are considered: (A) C1 = 0 and Ec = 0.6 kPa ; (B) C1 = 0 and ; (C) C1 = 0.1 and Ec = 0.6 kPa ; (D) C1 = 0.1 and . Within each subfigure, the rows represent , , and on a cross-section of the plane x1 = 0 of the axisymmetric cell, and the columns represent . Parameter values as in Table 1.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1013305.g005