PoweREST: Statistical power estimation for spatial transcriptomics experiments to detect differentially expressed genes between two conditions
Fig 4
Power estimation based on the CRC dataset.
(A and B) Histologically annotated carcinoma and carcinoma border areas in (A) an MSS sample and (B) an MSI-H sample. (C) The fitted power surfaces using P-splines for DE analysis within the carcinoma border with the number of slice replicates per group being 2, 4, and 6. (D) The relationship between the power and logFC in gene expression with slice replicates from 1 to 10 for the percentage of spots with the detected gene being 0.05, 0.10, and 0.15.