PoweREST: Statistical power estimation for spatial transcriptomics experiments to detect differentially expressed genes between two conditions
Fig 1
Schema of the proposed PoweREST method.
When a preliminary cohort of ST data is available, PoweREST performs the power calculation based on bootstrap and P-splines fitting. When preliminary data are not available, an R Shiny app with power estimation results based on datasets from two cancer studies can be used. Created in BioRender. Shui, L. (2025) https://BioRender.com/injyq0j.