Barking up the right tree: Immune checkpoint signatures of human and dog cancers
Fig 2
Dendrogram representing the hierarchical clustering of a distance matrix that compares canine and human cancers with respect to their immune checkpoint (IC) expression levels.
Cancers grouped predominantly within their respective species (bold font - canine, normal font - human). However, notable interspecies similarities emerged, particularly between canine and human gliomas and between canine osteosarcoma and human sarcoma. The figure also illustrates that human cancers tend to cluster according to their histological subtype and primary cancer site. Colors distinguish 14 different clusters. For detailed distance values, refer to S4 Table.