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Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity

Fig 12

Pattern completion task and results.

(A) Pattern completion task and results. Two orthogonal inputs (A and B, overlap = 0) are presented simultaneously during the encoding. During the retrieval, 100 cues are constructed with linearly varying similarity to A and B (overlaps sum to 1), each presented for 7.2 s (30 phases) without further learning. (B) Learned Rc weight matrix after training on A and B. (C) Retrieval performance versus cue similarity to A ( A–Cue). Performance is measured by the probability of retrieving A (blue) or B (purple) across 30 phases. (D) Change in neural representation ( output) versus cue discrimination (( A–Cue), averaged over 30 phases.

Fig 12

doi: https://doi.org/10.1371/journal.pcbi.1013267.g012