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Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity

Fig 7

Impact of the direct PP on retrieval.

(A) Illustration of different percentages of partial cues for a learned input A. (B) Firing rate heatmap for CA3 neurons in response to each cue during retrieval (120 ms). Each heatmap shows the most common firing pattern across 20 trials for that cue. (B1) With the direct PP intact, firing patterns are consistent across cue variations. (B2) With the direct path silenced, firing patterns vary strongly with each cue. (C) Retrieval performance versus percentage of cue under two conditions: with direct PP (blue) and without direct PP (red). Each point is the mean success rate (averaged over 5 random cues 20 repeats; 100% cue uses one sample).

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1013267.g007