Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity
Fig 6
Retrieval of learned memories.
(A) Spike raster during retrieval in response to a cue similar to inputs E and G out of the 10 encoded patterns A to J. Layer conventions are the same as in Fig 3B. The cue is presented in 10 trials; some yield successful recall of E or G (indicated by strong firing in deep EC for those patterns), while others fail. (B) CA3 engram firing rates during retrieval for the example trials. (B1) Successful retrieval of pattern G: the CA3 G-engrams dominate firing. (B2) Successful retrieval of pattern E: the CA3 E-engrams dominate. (B3) Retrieval failure: no single engram dominates, and activity remains low and diffuse.