CellMet: Extracting 3D shape and topology metrics from confluent cells within tissues
Fig 3
Application to Drosophila gastrulation.
A. Multi orthoview of PH-mCherry embryo during mesoderm invagination from Gracia [57] (left) and cell identity (right). B. Colour coded cells show volume (left) and neighbour number (right) in the embryo. C. Scheme showing tissue invagination (left) and the corresponding connectivity graph from A (right). The top row is before gastrulation and bottom row is during gastrulation. Node colour represents the number of neighbours and edge colour represents the link between two cells. D. Violin plot of the number of neighbours from C. Measures made in 2D at the apical cell surface (brown) and in 3D (cyan). cells from one embryo.