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Impact of ligand binding on VEGFR1, VEGFR2, and NRP1 localization in human endothelial cells

Fig 7

Impact of VEGFR1 on A,B, Surface and C,D, Internal VEGFR2 ligation by VEGF165a.

Changes in VEGFR2.VEGF165a.VEGFR2 levels under varying VEGF165a concentrations. Change in VEGFR2.VEGF165a. VEGFR2 levels under loss of VEGFR1 molecules and under varying VEGF165a concentrations. When VEGFR1 is removed, surface VEGFR2.VEGF165a.VEGFR2 does not change but internal VEGFR2.VEGF165a.VEGFR2 levels change over a range of VEGF165a concentrations.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1013254.g007