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Impact of ligand binding on VEGFR1, VEGFR2, and NRP1 localization in human endothelial cells

Fig 4

Distribution of ligated and active VEGFR1 and VEGFR2 receptors following addition of one ligand.

A-C, Cell surface (A), internal (B), and whole cell (C) VEGFR2 following 50 ng.ml-1 VEGF121a or VEGF165a, D-F, cell surface (D), internal (E), and whole cell (F) VEGFR1 following 50 ng.mL-1 VEGF121a, VEGF165a, PLGF1 or PLGF2. V165 represents VEGF165a, V121 represents VEGF121a, P1 represents PLGF1, and P2 represents PLGF2.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1013254.g004