Parameterization of intraoperative human microelectrode recordings: Linking action potential morphology to brain anatomy
Fig 10
Local field potential isolation using spike parameterization and removal.
(A) Example raw voltage trace from a microelectrode recording site. (B) zoomed in raw voltage trace. (C) Two sorted units parameterized and plotted on the filtered voltage trace. (D) subtracting the parameterized spikes from the unfiltered trace isolates the local field potential. (E) Power spectral density was calculated from the raw and LFP signal with spikes removed. (F) Average 200–300 Hz band power at 6 different recording sites from the raw signal (black) and LFP (Green). (G) Spike removal at 6 recording sites from one MER track showed to a significant reduction in 200–300 Hz band power by approximately 25% (paired t-test, t(5) = 5.37, *p = 0.003).