Parameterization of intraoperative human microelectrode recordings: Linking action potential morphology to brain anatomy
Fig 9
Capturing pulse-modulated firing using .
(A) Raw signal traces from the motor thalamus microelectrode recording and EKG. (B) a single cardiac cycle was isolated (-0.1 to 0.9 from R-wave) with two parameterized units. (C) The mean of each parameterized spike was plotted in reference to the aligned R-wave of the average EKG signal. An impulse-response function was fitted to the baselined distribution using a nonlinear least square fitting algorithm using the trust-region-reflective method in the form
. Unit 1 shows clear impulse-response-like pulse modulation (
; n = 2.33; m = 9.60;
), whereas unit 2 did not show cardiac-tuning (A = 24.79; n = 0.67; m = -2.95;
).
values show that unit 1 is pulse-modulated, while unit 2 is not.