Electrodiffusion dynamics in the cardiomyocyte dyad at nano-scale resolution using the Poisson-Nernst-Planck (PNP) equations
Fig 14
RyR activation time for different values of the dyad width (Li) and the intracellular Ca2+ diffusion coefficient ().
The RyR activation time is defined as time from the membrane Ca2+ channel is opened until the Ca2+ concentration outside of an apposing RyR channel reaches 0.5 M. We perform PNP model simulations similar to the one displayed in Fig 11. We use
ns and an adaptive mesh like illustrated in Fig 3.