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Computational modeling of ketamine-induced changes in gamma-band oscillations: The contribution of parvalbumin and somatostatin interneurons

Fig 5

Gamma-band power and aperiodic components of simulated data with NMDA-R reductions.

Panels (A-C) depict the averaged power spectrum of the fast-Fourier transformed data in the gamma-power range. Panels (D-F) show the aperiodic component of the power spectrum in log-log space. Shaded envelopes indicate standard error. Control condition (black, dotted line) without any manipulations. In the test conditions (straight, colored lines), NMDA receptors of (A, D) parvalbumin neurons, PV, (B, E) somatostatin neurons, SST, (C, F) vasoactive-intestinal peptide neurons, VIP, and pyramidal neurons, Pyr, and in all aforementioned neuron types simultaneously, were reduced by the indicated amount.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1013118.g005