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MaxComp: Predicting single-cell chromatin compartments from 3D chromosome structures

Fig 2

Selected example of model compartments predicted by MaxComp and the corresponding structures of H1-hESC Chr6

(A) The predicted compartments for structure 35, 115, 255, 361, 443 of H1-hESC Chr6 together with the input adjacency matrices of the MaxComp approach. (B) The compartment profile and 3D visualization of structure 35, 115, 255, 361, 443 of H1-hESC Chr6 colored by compartments (red in compartment A and blue in compartment B) from both experiment and the MaxComp prediction showed together with the nucleus envelope. (C) Predicted speckles (green) showed together with the single-cell examples colored compartments labeled by MaxComp and the Hi-C-based PCA.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1013114.g002