Inferring synaptic transmission from the stochastic dynamics of the quantal content: An analytical approach
Fig 7
Identification of release and refilling probabilities for MNTB-LSO synapses using QC fluctuation statistics.
The left-most-plot marks the region of parameter space (in terms of the refilling and release probabilities pd and pr, respectively) consistent with a steady-state QC Fano factor as predicted by the formula (16) to be less than . The FF upper bound is based on a
range around the experimentally-observed
in Fig 5C. The other plots mark the parameter space consistent with QC correlations as given by (20) to be
and the normalized synaptic depression as given by (13) in the range
based on the electrophysiological data in Fig 5. The right-most-plot shows the intersection of all three consistent regions narrowing the parameter space to a region with a high release probability (
) and
.