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Expectation generation and its effect on subsequent pain and visual perception

Fig 6

ROI results.

(A) ROIs are shown with a contour for each modality (rows) and processing stage (columns). Regions with higher activity for more intense stimuli are presented with a green contour. Regions with a significant cue mean effect are presented in red (higher activity for higher cue mean) or blue (higher activity for lower cue mean). (B) The ROI score in the two regions with significant cue mean effect during pain perception (including other parts of the NAc) as a function of the stimulus intensity level (x axis) and cue mean (color). Bars represent means across participants, error bars represent standard error of the mean across participants, and points represent single participants. Asterisks represent the level of significance (* p < .05, *** p < .001). Abbreviations: aIns = anterior insula; aMCC = anterior midcingulate cortex; dlPFC = dorsolateral prefrontal cortex; dpIns = dorsal posterior insula; L = left; Med = medial; NAc = nucleus accumbens; OFC = orbitofrontal cortex; PAG = periaqueductal gray; R = right; thal = thalamus.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1013053.g006