How are estimated cellular turnover rates influenced by the dynamics of a source population?
Table 2
Summary of the approximations for the label gain and loss rates in the POI provided here for different scenarios. A POI with a precursor population has four qualitatively different gain and loss rate scenarios. These approximations underscore how crucial it is to know the precursor’s dynamics in identifying the true turnover rate of the POI. The special cases are derived in Equations 6 and 7, while the regular cases are derived in Equations 9 and 11.