InteracTor: Feature engineering and explainable AI for profiling protein structure-interaction-function relationships
Fig 5
Machine learning benchmark across different feature sets.
A) F1 scores were computed for several classification models (shown as colored bars) across different feature sets. Feature sets were ranked by their impact on model performance, with higher F1 scores indicating superior predictive accuracy. B) Performance of the best model (Histogram Gradient Boosting) across different feature sets, showing mean validation accuracy after 5 runs.