Distinguishing multiple roles of T cell and macrophage involvement in determining lymph node fates during Mycobacterium tuberculosis infection
Fig 10
Predicting drivers of Mtb-specific T-cell efflux: comparing LTBI and active hosts using sensitivity analysis of Mtb-specific T-cell efflux.
Left panels contain data from 2000 individual simulated diseased LNs and right panels contain data from 3000 individual simulated uninfected/activated LNs. All simulated LNs are from the same set of 1000 virtual hosts. Shading indicates correlation between parameter and FDG avidity during time interval t (given a parameter is at least significant for 30 days in t). White boxes indicate not significantly correlated at any time points in t. A blue color indicates a positive correlation, and red color indicates a negative correlation. Significance alpha = 0.01 after Bonferroni correction. Complete model state descriptions (MR, MI, E4, etc.) can be found in Table 2 and parameters in Tables A, B, and C in S2 Appendix.